FA2H Polyclonal Antibody

• Background:

  FA2H encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in FA2H have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.

• Description:

  Rabbit Anti-FA2H Polyclonal Antibody

• Product Name Alternative:

  Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase

• Gene ID:

  79152

• Accession Number:

  Q7L5A8

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from part region of human FA2H protein at amino acid sequence of 101-150

• Clonality:

  Polyclonal

• Tag:

  FA2H

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  55kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of FA2H

• Observed Molecular Weight:

  55

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000

• Other Product Names:

  Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q7L5A8

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG