ERAP2 Polyclonal Antibody

• Background :

  ERAP2 encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5.

• Description :

  Rabbit Anti-ERAP2 Polyclonal Antibody

• Product Name Alternative :

  Endoplasmic reticulum aminopeptidase 2; Leukocyte-derived arginine aminopeptidase; L-RAP

• Gene ID :

  64167

• Accession Number :

  Q6P179

• Reactivity :

  Human

• Immunogen :

  Synthesized peptide derived from part region of human ERAP2 protein

• Clonality :

  Polyclonal

• Tag :

  ERAP2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  105kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of ERAP2 protein

• Observed Molecular Weight :

  105

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Endoplasmic reticulum aminopeptidase 2; Leukocyte-derived arginine aminopeptidase; L-RAP

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q6P179

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG