Products for Research Use Only
RegisterLogin

Dsg1 Polyclonal Antibody

CAT: 0749-ABP58426-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP58426-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
DSG1 encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. DSG1 is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of DSG1 has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
Description
Rabbit Anti-Dsg1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Desmoglein-1; Cadherin family member 4; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen
Gene ID
1828
Accession Number
Q02413
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human Dsg1 protein at amino acid sequence of 30-90
Clonality
Polyclonal
Tag
Dsg1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
160kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of Dsg1
Observed Molecular Weight
160
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:500-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Desmoglein-1; Cadherin family member 4; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q02413
Isotype
Rabbit IgG

Related Products

CatalogName
ANT-11920-50ugDSG1 / Desmoglein-1 Polyclonal Antibody
ANT-11920-100ugDSG1 / Desmoglein-1 Polyclonal Antibody
ANT-11919-100ugDSG1 / 3 Monoclonal Antibody
ANT-11919-50ugDSG1 / 3 Monoclonal Antibody
ANT-35829-100ugHuman DSG1/Desmoglein-1 Antibody
PPT-12349Human DSG1 Recombinant Protein
PPT-12353Human DSG1/Desmoglein-1 Recombinant Protein
KTE61975-01ELISA kit for Human Desmogleins 1 (DSG1)  Kit
ABP58428-01DSG4 Polyclonal Antibody
ANT-11923-100ugDSG2 Polyclonal Antibody

Alternative Products

CatalogName
JOT-AP08633-01Dsg1 Polyclonal Antibody

Popular Products