DRD2 Polyclonal Antibody

• Background:

  DRD2 encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in DRD2 causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of DRD2 results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

• Description:

  Rabbit Anti-DRD2 Polyclonal Antibody

• Product Name Alternative:

  D; 2dopamine receptor; Dopamine D2 receptor

• Gene ID:

  1813

• Accession Number:

  P14416

• Reactivity:

  Human, Rat

• Immunogen:

  Synthesized peptide derived from part region of human DRD2 protein at amino acid sequence of 170-250

• Clonality:

  Polyclonal

• Tag:

  DRD2

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  48kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of DRD2 protein

• Observed Molecular Weight:

  48

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  D; 2dopamine receptor; Dopamine D2 receptor

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P14416

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG