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DMBT1 Polyclonal Antibody

CAT: 0749-ABP58390-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58390-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0 , 7.5 , and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID) . Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Description
Rabbit Anti-DMBT1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Deleted in malignant brain tumors 1 protein; Glycoprotein 340; Gp-340; Hensin; Salivary agglutinin; SAG
Gene ID
1755
Accession Number
Q9UGM3
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human DMBT1 protein
Clonality
Polyclonal
Tag
DMBT1
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
265kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DMBT1 protein
Observed Molecular Weight
265
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Deleted in malignant brain tumors 1 protein; Glycoprotein 340; Gp-340; Hensin; Salivary agglutinin; SAG
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UGM3
Isotype
Rabbit IgG

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