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DLG3 Polyclonal Antibody

CAT: 0749-ABP58382-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58382-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DLG3 (Discs Large MAGUK Scaffold Protein 3) is a Protein Coding gene. Diseases associated with DLG3 include X-Linked Non-Specific Intellectual Disability and Non-Syndromic Intellectual Disability. Among its related pathways are PI3K-Akt signaling pathway and Protein-protein interactions at synapses. DLG3 encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.
Description
Rabbit Anti-DLG3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Disks large homolog 3; Neuroendocrine-DLG; Synapse-associated protein 102; SAP-102; SAP102
Gene ID
1741
Accession Number
Q92796
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human DLG3 protein
Clonality
Polyclonal
Tag
DLG3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
89kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DLG3 protein
Observed Molecular Weight
89
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Disks large homolog 3; Neuroendocrine-DLG; Synapse-associated protein 102; SAP-102; SAP102
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92796
Isotype
Rabbit IgG

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