DKK2 Polyclonal Antibody

• Background :

  DKK2 encodes Dickkopf WNT Signaling Pathway Inhibitor 2 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6) .

• Description :

  Rabbit Anti-DKK2 Polyclonal Antibody

• Product Name Alternative :

  Dickkopf-related protein 2; Dickkopf-2; Dkk-2; hDkk-2

• Gene ID :

  27123

• Accession Number :

  Q9UBU2

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human DKK2 protein

• Clonality :

  Polyclonal

• Tag :

  DKK2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  28kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of DKK2 protein

• Observed Molecular Weight :

  28

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Dickkopf-related protein 2; Dickkopf-2; Dkk-2; hDkk-2

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q9UBU2

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG