DKK2 Polyclonal Antibody

CAT: 0749-ABP58377-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58377-01Size:30 µL
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Background
DKK2 encodes Dickkopf WNT Signaling Pathway Inhibitor 2 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6) .
Description
Rabbit Anti-DKK2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Dickkopf-related protein 2; Dickkopf-2; Dkk-2; hDkk-2
Gene ID
27123
Accession Number
Q9UBU2
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human DKK2 protein
Clonality
Polyclonal
Tag
DKK2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
28kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DKK2 protein
Observed Molecular Weight
28
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Dickkopf-related protein 2; Dickkopf-2; Dkk-2; hDkk-2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UBU2
Isotype
Rabbit IgG

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