DIRA3 Polyclonal Antibody

CAT: 0749-ABP58373-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58373-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DIRAS3 encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The DIRAS Family GTPase 3 acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. DIRAS3 (DIRAS Family GTPase 3) is a Protein Coding gene. Among its related pathways are Phospholipase-C Pathway and Development ERBB-family signaling.
Description
Rabbit Anti-DIRA3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GTP-binding protein Di-Ras3; Distinct subgroup of the Ras family member 3; Rho-related GTP-binding protein RhoI
Gene ID
9077
Accession Number
O95661
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human DIRA3 protein
Clonality
Polyclonal
Tag
DIRA3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
25kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DIRA3 protein
Observed Molecular Weight
25
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
GTP-binding protein Di-Ras3; Distinct subgroup of the Ras family member 3; Rho-related GTP-binding protein RhoI
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O95661
Isotype
Rabbit IgG

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