DHB8 Polyclonal Antibody

• Background :

  In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The Hydroxysteroid 17-Beta Dehydrogenase 8 encoded by HSD17B8 is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

• Description :

  Rabbit Anti-DHB8 Polyclonal Antibody

• Product Name Alternative :

  Estradiol 17-beta-dehydrogenase 8; 17-beta-hydroxysteroid dehydrogenase 81 Publication; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit1 Publication; KAR alpha subunit1 Publication; 3-oxoacyl-[acyl-carrier-protein] reductase Protein Ke6; Ke-6; Really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8

• Gene ID :

  7923

• Accession Number :

  Q92506

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human DHB8 protein

• Clonality :

  Polyclonal

• Tag :

  DHB8

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  28kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of DHB8 protein

• Observed Molecular Weight :

  28

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Estradiol 17-beta-dehydrogenase 8; 17-beta-hydroxysteroid dehydrogenase 81 Publication; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit1 Publication; KAR alpha subunit1 Publication; 3-oxoacyl-[acyl-carrier-protein] reductase Protein Ke6; Ke-6; Really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q92506

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG