CRLF1 Polyclonal Antibody

CAT: 0749-ABP58270-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58270-01Size:30 µL
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Background
CRLF1 (Cytokine Receptor Like Factor 1) is a Protein Coding gene. Diseases associated with CRLF1 include Cold-Induced Sweating Syndrome 1 and Crlf1-Related Cold-Induced Sweating Syndrome Including Crisponi Syndrome. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in CRLF1 result in Crisponi syndrome and cold-induced sweating syndrome.
Description
Rabbit Anti-CRLF1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Cytokine receptor-like factor 1; Cytokine-like factor 1; ZcytoR5
Gene ID
9244
Accession Number
O75462
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human CRLF1 protein at amino acid sequence of 50-130
Clonality
Polyclonal
Tag
CRLF1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
46kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CRLF1 protein
Observed Molecular Weight
46
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Cytokine receptor-like factor 1; Cytokine-like factor 1; ZcytoR5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O75462
Isotype
Rabbit IgG

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