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CIRBP Polyclonal Antibody

CAT: 0749-ABP58158-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58158-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CIRBP (Cold Inducible RNA Binding Protein) is a Protein Coding gene. Diseases associated with CIRBP include Cryptorchidism. Among its related pathways are DNA Damage and Translational Control. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity) . Promotes assembly of stress granules (SGs), when overexpressed.
Description
Rabbit Anti-CIRBP Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Cold-inducible RNA-binding protein; A18 hnRNP; Glycine-rich RNA-binding protein CIRP
Gene ID
1153
Accession Number
Q14011
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human CIRBP protein
Clonality
Polyclonal
Tag
CIRBP
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
18kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CIRBP protein
Observed Molecular Weight
18
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Cold-inducible RNA-binding protein; A18 hnRNP; Glycine-rich RNA-binding protein CIRP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14011
Isotype
Rabbit IgG

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