CHD6 Polyclonal Antibody

• Background:

  CHD6 (Chromodomain Helicase DNA Binding Protein 6) is a Protein Coding gene. Diseases associated with CHD6 include Pitt-Hopkins Syndrome and Developmental Coordination Disorder. CHD6 encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication.

• Description:

  Rabbit Anti-CHD6 Polyclonal Antibody

• Product Name Alternative:

  Chromodomain-helicase-DNA-binding protein 6; CHD-6; ATP-dependent helicase CHD6; Radiation-induced gene B protein

• Gene ID:

  84181

• Accession Number:

  Q8TD26

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human CHD6 protein

• Clonality:

  Polyclonal

• Tag:

  CHD6

• Applications:

  IHC, IF

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  298kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of CHD6 protein

• Observed Molecular Weight:

  298

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200

• Other Product Names:

  Chromodomain-helicase-DNA-binding protein 6; CHD-6; ATP-dependent helicase CHD6; Radiation-induced gene B protein

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q8TD26

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG