CCL1 Polyclonal Antibody

• Background :

  CCL1 (C-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CCL1 include Igg4-Related Sclerosing Cholangitis and Tolosa-Hunt Syndrome. Among its related pathways are Akt Signaling and PEDF Induced Signaling. This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.

• Description :

  Rabbit Anti-CCL1 Polyclonal Antibody

• Product Name Alternative :

  C-C motif chemokine 1; Small-inducible cytokine A1; T lymphocyte-secreted protein I-309

• Gene ID :

  6346

• Accession Number :

  P22362

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human CCL1 protein at amino acid sequence of 20-100

• Clonality :

  Polyclonal

• Tag :

  CCL1

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  10kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of CCL1 protein

• Observed Molecular Weight :

  10

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  C-C motif chemokine 1; Small-inducible cytokine A1; T lymphocyte-secreted protein I-309

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P22362

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG