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BTN3A1/2/3 Polyclonal Antibody

CAT: 0749-ABP57930-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57930-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) -associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g. BTN2A1; MIM 613590) and BTN3 (e.g. BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al. 2010 [PubMed 20208008]) . BTN3A1 (Butyrophilin Subfamily 3 Member A1) is a Protein Coding gene. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Butyrophilin (BTN) family interactions. An important paralog of BTN3A1 is BTN3A3.
Description
Rabbit Anti-BTN3A1/2/3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
Gene ID
11119
Accession Number
O00481/P78410/O00478
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human BTN3A1/2/3 protein at amino acid sequence of 41-90
Clonality
Polyclonal
Tag
BTN3A1/2/3
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of BTN3A1/2/3
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O00481
Isotype
Rabbit IgG

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