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BRD2 Polyclonal Antibody

CAT: 0749-ABP57923-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57923-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BRD2 gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21. , but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
Description
Rabbit Anti-BRD2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein
Gene ID
6046
Accession Number
P25440
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human BRD2 protein
Clonality
Polyclonal
Tag
BRD2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
88kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of BRD2 protein
Observed Molecular Weight
88
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P25440
Isotype
Rabbit IgG

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