BIRC2 Polyclonal Antibody

• Background :

  The protein encoded by BIRC2 gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description :

  Rabbit Anti-BIRC2 Polyclonal Antibody

• Product Name Alternative :

  Baculoviral IAP repeat-containing protein 2; Cellular inhibitor of apoptosis 1; C-IAP1; IAP homolog B; Inhibitor of apoptosis protein 2; hIAP-2; hIAP2; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2

• Gene ID :

  329

• Accession Number :

  Q13490

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human BIRC2 protein

• Clonality :

  Polyclonal

• Tag :

  BIRC2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  67kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of BIRC2 protein

• Observed Molecular Weight :

  67

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Baculoviral IAP repeat-containing protein 2; Cellular inhibitor of apoptosis 1; C-IAP1; IAP homolog B; Inhibitor of apoptosis protein 2; hIAP-2; hIAP2; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q13490

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG