ASPP1 Polyclonal Antibody

CAT: 0749-ABP57827-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57827-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PPP1R13B encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. PPP1R13B (Protein Phosphatase 1 Regulatory Subunit 13B) is a Protein Coding gene. Among its related pathways are Activation of BH3-only proteins and TP53 Regulates Transcription of Cell Death Genes.
Description
Rabbit Anti-ASPP1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Apoptosis-stimulating of p53 protein 1; Protein phosphatase 1 regulatory subunit 13B
Gene ID
23368
Accession Number
Q96KQ4
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human ASPP1 protein at amino acid sequence of 630-680
Clonality
Polyclonal
Tag
ASPP1
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ASPP1
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Apoptosis-stimulating of p53 protein 1; Protein phosphatase 1 regulatory subunit 13B
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q96KQ4
Isotype
Rabbit IgG

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