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ASPM Polyclonal Antibody

CAT: 0749-ABP57826-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57826-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ASPM is the human ortholog of the Drosophila melanogaster ‘abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene. ASPM (Abnormal Spindle Microtubule Assembly) is a Protein Coding gene. Diseases associated with ASPM include Microcephaly 5, Primary, Autosomal Recessive and Primary Microcephaly.
Description
Rabbit Anti-ASPM Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Abnormal spindle-like microcephaly-associated protein; Abnormal spindle protein homolog; Asp homolog
Gene ID
259266
Accession Number
Q8IZT6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human ASPM protein at amino acid sequence of 1230-1310
Clonality
Polyclonal
Tag
ASPM
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
382kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ASPM protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Abnormal spindle-like microcephaly-associated protein; Abnormal spindle protein homolog; Asp homolog
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8IZT6
Isotype
Rabbit IgG

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