RegisterLogin

ACVR1 Polyclonal Antibody

CAT: 0749-ABP57701-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57701-01Size:30 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
Description
Rabbit Anti-ACVR1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Activin receptor type-1; Activin receptor type I; ACTR-I; Activin receptor-like kinase 2; ALK-2; Serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; TSR-I
Gene ID
90
Accession Number
Q04771
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human ACVR1 protein
Clonality
Polyclonal
Tag
ACVR1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
55kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ACVR1 protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Activin receptor type-1; Activin receptor type I; ACTR-I; Activin receptor-like kinase 2; ALK-2; Serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; TSR-I
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q04771
Isotype
Rabbit IgG

Related Products

CatalogName
PPT-10345Human ACVR1 Recombinant Protein
KTE60903-01Human Activin receptor type-1 (ACVR1) ELISA Kit
ANT-10067-100ugACVR1B Polyclonal Antibody
ANT-10067-50ugACVR1B Polyclonal Antibody
ANT-10069-100ugACVRL1 Polyclonal Antibody
ANT-10069-50ugACVRL1 Polyclonal Antibody
ANT-35541-100ugHuman ACVR1C Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-13843-50ugPolyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody

Alternative Products

CatalogName
RA31005-01ACVR1 Polyclonal Antibody
APR14808GPolyclonal ACVR1 Antibody
E10G08017ACVR1 Rabbit Polyclonal Antibody
AP05119PU-NACVR1 Sheep Polyclonal Antibody
HC323014-01Anti-ACVR1 Polyclonal Antibody
APR14914GPolyclonal ALK2 / ACVR1 Antibody (Internal)
MBS8118928-01Anti-ACVR1 Antibody, Rabbit Polyclonal
TA349649Rabbit Polyclonal Anti-ACVR1 Antibody
PAV309Rabbit Anti-ACVR1 Polyclonal Antibody
E10G31342Mouse Acvr1 Rabbit Polyclonal Antibody

Popular Products