ACHB3 Polyclonal Antibody

• Background :

  CHRNB3 (Cholinergic Receptor Nicotinic Beta 3 Subunit) is a Protein Coding gene. Diseases associated with CHRNB3 include Duane Retraction Syndrome and Autosomal Dominant Nocturnal Frontal Lobe Epilepsy. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Acetylcholine Binding And Downstream Events. The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel.

• Description :

  Rabbit Anti-ACHB3 Polyclonal Antibody

• Product Name Alternative :

  Neuronal acetylcholine receptor subunit beta-3

• Gene ID :

  1142

• Accession Number :

  Q05901

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from part region of human ACHB3 protein at amino acid sequence of 160-240

• Clonality :

  Polyclonal

• Tag :

  ACHB3

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  50kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of ACHB3 protein

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Neuronal acetylcholine receptor subunit beta-3

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q05901

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG