IL-31 Polyclonal Antibody

• Background:

  IL31 (interleukin 31), which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.

• Description:

  Rabbit Anti-IL-31 Polyclonal Antibody

• Product Name Alternative:

  Interleukin-31; IL-31

• Gene ID:

  386653

• Accession Number:

  Q6EBC2

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide from human protein at AA range: 21-70

• Clonality:

  Polyclonal

• Tag:

  Interleukin-31 (IL-31)

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous IL-31.

• Observed Molecular Weight:

  65

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200

• Other Product Names:

  Interleukin-31; IL-31

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q6EBC2

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG