Synapsin-1 Polyclonal Antibody

CAT: 0749-ABP57418-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57418-01Size:30 µL
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Background
SYN1 (synapsin I) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in SYN1 may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Description
Rabbit Anti-Synapsin-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SYN1; Synapsin-1; Brain protein 4.1; Synapsin I
Gene ID
6853
Accession Number
P17600
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Synapsin-1
Clonality
Polyclonal
Tag
Synapsin-1
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
75kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Synapsin-1 Polyclonal Antibody detects endogenous levels of Synapsin-1 protein.
Observed Molecular Weight
75
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
SYN1; Synapsin-1; Brain protein 4.1; Synapsin I
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P17600
Isotype
Rabbit IgG

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