Products for Research Use Only
RegisterLogin

P300 Polyclonal Antibody

CAT: 0749-ABP57381-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP57381-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
EP300 (E1A binding protein p300) encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Description
Rabbit Anti-p300 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
Gene ID
2033
Accession Number
Q09472
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human p300
Clonality
Polyclonal
Tag
Histone acetyltransferase p300
Applications
IF, WB, IHC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
300kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
P300 Polyclonal Antibody detects endogenous levels of p300 protein.
Observed Molecular Weight
300
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; Not yet tested in other applications
Other Product Names
EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q09472
Isotype
Rabbit IgG

Related Products

CatalogName
ABP57439-01P300 (Acetyl Lys1542) Polyclonal Antibody
ABP54122-01P300 (phospho Ser89) Polyclonal Antibody
ABP57440-01P300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody
KTE71393-01ELISA kit for Mouse Histone acetyltransferase p300 (EP300)
ANT-13745-50ugPhosphoprotein p30 / Pret-105 Polyclonal Antibody
ANT-13745-100ugPhosphoprotein p30 / Pret-105 Polyclonal Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody
ANT-13843-50ugPolyclonal Antibody

Alternative Products

CatalogName
MBS8526673-01p300 Polyclonal Antibody

Popular Products