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Cleaved-CD97β (S531) Polyclonal Antibody

CAT: 0749-ABP57098-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57098-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ADGRE5 (adhesion G protein-coupled receptor E5) encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of ADGRE5 may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
Description
Rabbit Anti-Cleaved-CD97β (S531) Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CD97; CD97 antigen; Leukocyte antigen CD97; CD antigen CD97
Gene ID
976
Accession Number
P48960
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human CD97β at AA range: 480-560
Clonality
Polyclonal
Tag
CD97 antigen
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
34kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Cleaved-CD97β (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97β protein resulting from cleavage adjacent to S531.
Observed Molecular Weight
34
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
CD97; CD97 antigen; Leukocyte antigen CD97; CD antigen CD97
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P48960
Isotype
Rabbit IgG

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