Per2 Polyclonal Antibody

• Background :

  PER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER2 may increase the risk of getting certain cancers and have been linked to sleep disorders.

• Description :

  Rabbit Anti-Per2 Polyclonal Antibody

• Product Name Alternative :

  PER2; KIAA0347; Period circadian protein homolog 2; hPER2; Circadian clock protein PERIOD 2

• Gene ID :

  8864

• Accession Number :

  O15055

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from human Per2 around the non-phosphorylation site of S662

• Clonality :

  Polyclonal

• Tag :

  Period circadian protein homolog 2

• Applications :

  IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  Per2 Polyclonal Antibody detects endogenous levels of Per2 protein.

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.

• Other Product Names :

  PER2; KIAA0347; Period circadian protein homolog 2; hPER2; Circadian clock protein PERIOD 2

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/O15055

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG