Products for Research Use Only
RegisterLogin

Actinin-α1 Polyclonal Antibody

CAT: 0749-ABP56861-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP56861-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 (actinin alpha 1) encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for ACTN1.
Description
Rabbit Anti-Actinin-α1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1
Gene ID
87
Accession Number
P12814
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human Actinin-α1 at AA range: 1-80
Clonality
Polyclonal
Tag
Alpha-actinin-1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
103kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Actinin-α1 Polyclonal Antibody detects endogenous levels of Actinin-α1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P12814
Isotype
Rabbit IgG

Related Products

CatalogName
ABP57260-01Actinin-Alpha1 Polyclonal Antibody
ABP50596-01Actinin-α3 Polyclonal Antibody
ABP0057Actinin-α1/2/3/4 Polyclonal Antibody
ABP50595-01Actinin-α2/3 Polyclonal Antibody
ABP50594-01Actinin-Alpha1/2/3/4 Polyclonal Antibody
ABM40266-01A-actinin Monoclonal Antibody (4A12)
KTE60898-01Human Alpha-Actinin 1 (ACTN-1) ELISA Kit
ANT-35540-100ugHuman ACTN4/Actinin alpha 4 Antibody
ABP50591-01Actin α1 Polyclonal Antibody
KTE70546-01ELISA kit for Mouse Alpha-actinin-3 (ACTN3)

Alternative Products

CatalogName
E44H01473Actinin-α1 Polyclonal Antibody
ES8259-01Actinin-α1 Rabbit Polyclonal Antibody
bs-34256RAlpha-actinin-1 Polyclonal Antibody
BS90023Actinin α polyclonal antibody
TMAB-02487-01Anti-Alpha-actinin-1 Polyclonal Antibody
NBP1-85791Rabbit Polyclonal alpha-Actinin 1 Antibody
GTR18520608-01Alpha-actinin-1 Rabbit Polyclonal Antibody
MBS2032441-01Actinin Alpha 1 (ACTN1) Polyclonal Antibody
TRV-006475-01Polyclonal Antibody to Actinin Alpha 1 (ACTN1)
GTR18307602Alpha Actinin 1 Rabbit Polyclonal Antibody

Popular Products