Products for Research Use Only

DDX3Y Polyclonal Antibody

CAT: 0749-ABP56846-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56846-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by DDX3Y (DEAD-box helicase 3, Y-linked) is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of DDX3Y is not complemented by DDX3X. Mutations in DDX3Y result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both DDX3Y and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
Rabbit Anti-DDX3Y Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
DDX3Y; DBY; ATP-dependent RNA helicase DDX3Y; DEAD box protein 3; Y-chromosomal
Gene ID
8653
Accession Number
O15523
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human DDX3Y at AA range: 10-90
Clonality
Polyclonal
Tag
ATP-dependent RNA helicase DDX3Y
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
DDX3Y Polyclonal Antibody detects endogenous levels of DDX3Y protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
DDX3Y; DBY; ATP-dependent RNA helicase DDX3Y; DEAD box protein 3; Y-chromosomal
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O15523
Isotype
Rabbit IgG