TMEM185A Polyclonal Antibody

CAT: 0749-ABP56762-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP56762-01Size:30 µL
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Background
The protein encoded by TMEM185A (transmembrane protein 185A) is predicted to be a transmembrane protein. TMEM185A is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of TMEM185A has been defined on the X chromosome.
Description
Rabbit Anti-TMEM185A Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TMEM185A; CXorf13; FAM11A; Transmembrane protein 185A; Protein FAM11A
Gene ID
84548
Accession Number
Q8NFB2
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human TMEM185A at AA range: 260-340
Clonality
Polyclonal
Tag
Transmembrane protein 185A
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
41kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
TMEM185A Polyclonal Antibody detects endogenous levels of TMEM185A protein.
Observed Molecular Weight
41
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
TMEM185A; CXorf13; FAM11A; Transmembrane protein 185A; Protein FAM11A
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8NFB2
Isotype
Rabbit IgG

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