ATRIP Polyclonal Antibody

• Background :

  ATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

• Description :

  Rabbit Anti-ATRIP Polyclonal Antibody

• Product Name Alternative :

  ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

• Gene ID :

  84126

• Accession Number :

  Q8WXE1

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from human ATRIP around the non-phosphorylation site of S224

• Clonality :

  Polyclonal

• Tag :

  ATR-interacting protein

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  86kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  ATRIP Polyclonal Antibody detects endogenous levels of ATRIP protein.

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.

• Other Product Names :

  ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q8WXE1

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG