MAP-9 Polyclonal Antibody

• Background:

  Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs) . The microtubule-associated proteins can be divided into two groups, structural and dynamic. The MAP proteins function to stimulate tubulin assembly, enhance microtubule stability, influence the spatial distribution of microtubules within cells and utilize microtubule polarity to translocate cellular components. MAP-9 (microtubule-associated protein 9), also known as ASAP, is a 647 amino acid cytoplasmic protein that is constitutively expressed during the cell cycle. MAP-9 localizes to microtubules in interphase, associates with the mitotic spindle during mitosis and localizes to the central body during cytokinesis. Involved in organization of the bipolar mitotic spindle, MAP-9 is required for bipolar spindle assembly, mitosis progression and cytokinesis. MAP-9 may be involved in stabilizing interphase microtubules. Two isoforms of MAP-9 are produced due to alternative splicing events.

• Description:

  Rabbit Anti-MAP-9 Polyclonal Antibody

• Product Name Alternative:

  MAP9; ASAP; Microtubule-associated protein 9; Aster-associated protein

• Gene ID:

  79884

• Accession Number:

  Q49MG5

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from the Internal region of human MAP-9 at AA range: 90-170

• Clonality:

  Polyclonal

• Tag:

  Microtubule-associated protein 9

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  75kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  MAP-9 Polyclonal Antibody detects endogenous levels of MAP-9 protein.

• Observed Molecular Weight:

  75

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.

• Other Product Names:

  MAP9; ASAP; Microtubule-associated protein 9; Aster-associated protein

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q49MG5

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG