Microcephalin Polyclonal Antibody

• Background:

  MCPH1 (microcephalin 1) encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in MCPH1 have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

• Description:

  Rabbit Anti-Microcephalin Polyclonal Antibody

• Product Name Alternative:

  MCPH1; Microcephalin

• Gene ID:

  79648

• Accession Number:

  Q8NEM0

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from the N-terminal region of human Microcephalin at AA range: 60-140

• Clonality:

  Polyclonal

• Tag:

  Microcephalin

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  93kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  Microcephalin Polyclonal Antibody detects endogenous levels of Microcephalin protein.

• Observed Molecular Weight:

  93

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200

• Other Product Names:

  MCPH1; Microcephalin

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q8NEM0

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG