VASP Polyclonal Antibody

CAT: 0749-ABP56484-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP56484-01Size:30 µL
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Background
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Description
Rabbit Anti-VASP Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
VASP; Vasodilator-stimulated phosphoprotein; VASP
Gene ID
7408
Accession Number
P50552
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human VASP around the non-phosphorylation site of T278
Clonality
Polyclonal
Tag
Vasodilator-stimulated phosphoprotein
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
40-46kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
VASP Polyclonal Antibody detects endogenous levels of VASP protein.
Observed Molecular Weight
40-46
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Other Product Names
VASP; Vasodilator-stimulated phosphoprotein; VASP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P50552
Isotype
Rabbit IgG

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