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TPH1 Polyclonal Antibody

CAT: 0749-ABP56445-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56445-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TPH1 (tryptophan hydroxylase 1) encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Description
Rabbit Anti-TPH1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1
Gene ID
7166
Accession Number
P17752
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human TPH1 around the non-phosphorylation site of S260
Clonality
Polyclonal
Tag
Tryptophan 5-hydroxylase 1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
51kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
TPH1 Polyclonal Antibody detects endogenous levels of TPH1 protein.
Observed Molecular Weight
51
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P17752
Isotype
Rabbit IgG

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