CD141 Polyclonal Antibody

• Background :

  The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

• Description :

  Rabbit Anti-CD141 Polyclonal Antibody

• Product Name Alternative :

  THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141

• Gene ID :

  7056

• Accession Number :

  P07204

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from the C-terminal region of human CD141 at AA range: 500-580

• Clonality :

  Polyclonal

• Tag :

  Thrombomodulin

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  100kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  CD141 Polyclonal Antibody detects endogenous levels of CD141 protein.

• Observed Molecular Weight :

  60

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.

• Other Product Names :

  THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P07204

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG