CD141 Polyclonal Antibody

CAT: 0749-ABP56387-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP56387-01Size:30 µL
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Background
The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.
Description
Rabbit Anti-CD141 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
Gene ID
7056
Accession Number
P07204
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human CD141 at AA range: 500-580
Clonality
Polyclonal
Tag
Thrombomodulin
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
100kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CD141 Polyclonal Antibody detects endogenous levels of CD141 protein.
Observed Molecular Weight
60
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P07204
Isotype
Rabbit IgG

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