ZM223 (hydrochloride)
CAT:
804-HY-101790A-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZM223 (hydrochloride)
- CAS Number: 2438679-27-5
- UNSPSC Description: ZM223 hydrochloride is an orally active, potent non-covalent NEDD8 activating enzyme (NAE) inhibitor with excellent anticancer activity[1].
- Target Antigen: NEDD8-activating Enzyme
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/zm223-hydrochloride.html
- Purity: 99.21
- Solubility: DMSO : 150 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=C(C(F)(F)F)C=C1)NC2=NC3=CC=C(NC(CSC4=CC=C(N)C=C4)=O)C=C3S2.[H]Cl
- Molecular Weight: 538.99
- References & Citations: [1]Ma H, et al. Discovery of benzothiazole derivatives as novel non-sulfamide NEDD8 activating enzyme inhibitors by target-based virtual screening. Eur J Med Chem. 2017 Jun 16;133:174-183.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported