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Glut3 Polyclonal Antibody

CAT: 0749-ABP56216-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56216-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GLUT3 (SLC2A3) belongs to the glucose transporter family (GLUTs) which mediates the transport of glucose across cellular membranes in mammalian cells. There are three subclasses within GLUTs: class I comprises the classical transporters GLUT1-4 and GLUT14; class II contains the "odd" isoforms GLUT5, 7, 9, and 11; the isoforms GLUT6, 8, 10, 12 and the proton driven myoinositol transporter HMIT (GLUT13) belong to class III. GLUT3 is considered as a neuron-specific glucose transporter because of its dominant expression in the brain in various species. However, besides the brain GLUT3 is also expressed in tissues with high demand for glucose such as sperm, preimplantation embryos, circulating white blood cells, and an array of carcinoma cell lines. ecently GLUT3 has been identified as a sensitive and specific marker for embyonal carcinomas and yolk tumors. he GLUT14 is believed to be the duplicate gene of GLUT3 given to the high identity in sequence between them. This antibody was generated against the internal region of human GLUT3 and may cross-react with GLUT14.
Description
Rabbit Anti-Glut3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SLC2A3; GLUT3; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3
Gene ID
6515
Accession Number
P11169
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human Glut3 at AA range: 420-500
Clonality
Polyclonal
Tag
Solute carrier family 2 facilitated glucose transporter member 3
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
55kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Glut3 Polyclonal Antibody detects endogenous levels of Glut3 protein.
Observed Molecular Weight
55
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
SLC2A3; GLUT3; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P11169
Isotype
Rabbit IgG

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