ENaC β Polyclonal Antibody

• Background :

  Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. SCNN1B (sodium channel epithelial 1 beta subunit) encodes the beta subunit, and mutations in SCNN1B have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

• Description :

  Rabbit Anti-ENaC β Polyclonal Antibody

• CAS Number :

  9007-83-4

• Product Name Alternative :

  SCNN1B; Amiloride-sensitive sodium channel subunit beta; Beta-NaCH; Epithelial Na (+) channel subunit beta; Beta-ENaC; ENaCB; Nonvoltage-gated sodium channel 1 subunit beta; SCNEB

• Gene ID :

  6338

• Accession Number :

  P51168

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from human ENaC β around the non-phosphorylation site of T615

• Clonality :

  Polyclonal

• Tag :

  Amiloride-sensitive sodium channel subunit beta

• Applications :

  IHC, IF, WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  72kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  ENaC β Polyclonal Antibody detects endogenous levels of ENaC β protein.

• Observed Molecular Weight :

  72

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

• Other Product Names :

  SCNN1B; Amiloride-sensitive sodium channel subunit beta; Beta-NaCH; Epithelial Na (+) channel subunit beta; Beta-ENaC; ENaCB; Nonvoltage-gated sodium channel 1 subunit beta; SCNEB

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P51168

• Isotype :

  Rabbit IgG