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RFC2 Polyclonal Antibody

CAT: 0749-ABP56040-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP56040-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RFC2 encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. RFC2 encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of RFC2 is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of RFC2 has been defined on chromosome 2.
Description
Rabbit Anti-RFC2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
RFC2; Replication factor C subunit 2; Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40
Gene ID
5982
Accession Number
P35250
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human RFC2 at AA range: 100-180
Clonality
Polyclonal
Tag
Replication factor C subunit 2
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
40kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
RFC2 Polyclonal Antibody detects endogenous levels of RFC2 protein.
Observed Molecular Weight
40
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
RFC2; Replication factor C subunit 2; Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P35250
Isotype
Rabbit IgG

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