RelB Polyclonal Antibody

CAT: 0749-ABP56029-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP56029-01Size:30 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Transcription factors of the nuclear factor κB (NF-κB) /Rel family play a pivotal role in inflammatory and immune responses. There are five family members in mammals: relA, c-Rel, RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52) . Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52, respectively. Rel proteins bind p50 and p52 to form dimeric complexes that bind DNA and regulate transcription. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. NIK and IKKα (IKK1) regulate the phosphorylation and processing of NF-κB2 (p100) to produce p52, which translocates to the nucleus.
Description
Rabbit Anti-RelB Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
RELB; Transcription factor RelB; I-Rel
Gene ID
5971
Accession Number
Q01201
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human RelB around the non-phosphorylation site of S552
Clonality
Polyclonal
Tag
Transcription factor RelB
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
62kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
RelB Polyclonal Antibody detects endogenous levels of RelB protein.
Observed Molecular Weight
62
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
RELB; Transcription factor RelB; I-Rel
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q01201
Isotype
Rabbit IgG

Related Products

CatalogName
ABP56028-01RelB (phospho Ser552) Polyclonal Antibody
PPT-14966Human RELB Recombinant Protein
KTE60810-01Human V-rel avian reticuloendotheliosis viral oncogene related B (RELB) ELISA Kit
ABP56792-01RELT Polyclonal Antibody
ANT-14136-100ugRELT Polyclonal Antibody
ANT-14133-50ugRELA Polyclonal Antibody
ABP60125-01REL1 Polyclonal Antibody
ABP60127-01RELN Polyclonal Antibody
ABP60126-01REL2 Polyclonal Antibody
ANT-14133-100ugRELA Polyclonal Antibody

Alternative Products

CatalogName
MBS2579140-01RELB Polyclonal Antibody
APR02961GPolyclonal RELB Antibody
APRab17008-01RelB Rabbit Polyclonal Antibody
TMAB-12182-01Anti-RelB Polyclonal Antibody

Popular Products