KCNT1 Polyclonal Antibody

CAT: 0749-ABP55923-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP55923-01Size:30 µL
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Background
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNT1 (potassium sodium-activated channel subfamily T member 1) encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in KCNT1 cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-KCNT1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1
Gene ID
57582
Accession Number
Q5JUK3
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human KCNT1 at AA range: 980-1060
Clonality
Polyclonal
Tag
Potassium channel subfamily T member 1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
140kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
KCNT1 Polyclonal Antibody detects endogenous levels of KCNT1 protein.
Observed Molecular Weight
140
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5JUK3
Isotype
Rabbit IgG

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