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SLC4A8/10 Polyclonal Antibody

CAT: 0749-ABP55885-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55885-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLC4A10 (solute carrier family 4 member 10) belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by SLC4A10 was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. SLC4A10 is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Description
Rabbit Anti-SLC4A8/10 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SLC4A8; KIAA0739; NBC; NBC3; NDCBE1; Electroneutral sodium bicarbonate exchanger 1; Electroneutral Na (+) -driven Cl-HCO3 exchanger; Solute carrier family 4 member 8; k-NBC3; SLC4A10; NCBE; Sodium-driven chloride bicarbonate exchanger; Solute
Gene ID
57282/9498
Accession Number
Q2Y0W8/Q6U841
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human SLC4A8/10 at AA range: 380-460
Clonality
Polyclonal
Tag
Electroneutral sodium bicarbonate exchanger 1
Applications
WB, IHC, IF, ELISA
Field of Research
Cancer#Cell Biology #Epigenetics#Metabonomics#Signal Transduction
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
140kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SLC4A8/10 Polyclonal Antibody detects endogenous levels of SLC4A8/10 protein.
Observed Molecular Weight
140
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
SLC4A8; KIAA0739; NBC; NBC3; NDCBE1; Electroneutral sodium bicarbonate exchanger 1; Electroneutral Na (+) -driven Cl-HCO3 exchanger; Solute carrier family 4 member 8; k-NBC3; SLC4A10; NCBE; Sodium-driven chloride bicarbonate exchanger; Solute
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q2Y0W8
Isotype
Rabbit IgG

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