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Axl Polyclonal Antibody

CAT: 0749-ABP55772-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55772-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6) . AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.
Description
Rabbit Anti-Axl Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene
Gene ID
558
Accession Number
P30530
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Axl around the non-phosphorylation site of Y697
Clonality
Polyclonal
Tag
Tyrosine-protein kinase receptor UFO
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
130kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Axl Polyclonal Antibody detects endogenous levels of Axl protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P30530
Isotype
Rabbit IgG

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