PP2A-B56-α Polyclonal Antibody

CAT: 0749-ABP55719-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP55719-01Size:30 µL
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Background
The product of PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha) belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. PPP2R5A encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for PPP2R5A.
Description
Rabbit Anti-PP2A-B56-α Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PPP2R5A; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PR61alpha; PP2A B subunit isoform R5-alpha
Gene ID
5525
Accession Number
Q15172
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human PP2A-B56-α at AA range: 290-370
Clonality
Polyclonal
Tag
Serine threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
57kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PP2A-B56-α Polyclonal Antibody detects endogenous levels of PP2A-B56-α protein.
Observed Molecular Weight
57
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
PPP2R5A; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PR61alpha; PP2A B subunit isoform R5-alpha
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q15172
Isotype
Rabbit IgG

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