BCAS3 Polyclonal Antibody

CAT: 0749-ABP55678-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP55678-01Size:30 µL
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AVAILABILITY: InStock
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Background
Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98% identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23. BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers. It is reported to be a target of metastasis associated protein-1 (MTA-1) . Further BCAS3 expression is also upregulated in grade III and IV glioblastomas where it is misexpressed in the tumor cells.
Description
Rabbit Anti-BCAS3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
BCAS3; Breast carcinoma-amplified sequence 3; GAOB1
Gene ID
54828
Accession Number
Q9H6U6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human BCAS3 at AA range: 660-740
Clonality
Polyclonal
Tag
Breast carcinoma-amplified sequence 3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
100kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
BCAS3 Polyclonal Antibody detects endogenous levels of BCAS3 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
BCAS3; Breast carcinoma-amplified sequence 3; GAOB1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9H6U6
Isotype
Rabbit IgG

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