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PHAX Polyclonal Antibody

CAT: 0749-ABP55571-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP55571-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Small nuclear and small nucleolar RNAs (snRNAs and snoRNAs) are essential components of snRNPs and snoRNPs, and have a critical role in the maturation of, respectively, mRNAs and rRNAs within the nucleus of eukaryotic cells. Complex and specific pathways exist for the assembly of snRNPs and snoRNPs, involving, nucleocytoplasmic transport of snRNAs and intranuclear transport between compartments of snoRNAs. In metazoa, a subset of spliceosomal snRNAs are exported from the nucleus after transcription. This export occurs in a large complex containing a snRNA, the nuclear cap binding complex (CBC), RanGTP, the leucine-rich nuclear export signal receptor CRM1/Xpo1, and the recently identified phosphoprotein PHAX (phosphorylated adaptor for RNA export) . PHAX contains a conserved single-stranded nucleic acid binding domain (RNA_GG_bind domain) with no sequence homology with any other known RNA-binding module [PMID: 15574332,11333016, 15574332].
Description
Rabbit Anti-PHAX Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PHAX; RNUXA; Phosphorylated adapter RNA export protein; RNA U small nuclear RNA export adapter protein
Gene ID
51808
Accession Number
Q9H814
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human PHAX at AA range: 110-190
Clonality
Polyclonal
Tag
Phosphorylated adapter RNA export protein
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
48kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PHAX Polyclonal Antibody detects endogenous levels of PHAX protein.
Observed Molecular Weight
48
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
PHAX; RNUXA; Phosphorylated adapter RNA export protein; RNA U small nuclear RNA export adapter protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9H814
Isotype
Rabbit IgG

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