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MRP-S33 Polyclonal Antibody

CAT: 0749-ABP55553-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55553-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. MRPS33 (mitochondrial ribosomal protein S33) encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q.
Description
Rabbit Anti-MRP-S33 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MRPS33; CGI-139; PTD003; 28S ribosomal protein S33; mitochondrial; MRP-S33; S33mt
Gene ID
51650
Accession Number
Q9Y291
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human MRP-S33 at AA range: 30-110
Clonality
Polyclonal
Tag
28S ribosomal protein S33 mitochondrial
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MRP-S33 Polyclonal Antibody detects endogenous levels of MRP-S33 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
MRPS33; CGI-139; PTD003; 28S ribosomal protein S33; mitochondrial; MRP-S33; S33mt
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y291
Isotype
Rabbit IgG

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