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MRP-L48 Polyclonal Antibody

CAT: 0749-ABP55551-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55551-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL48 (mitochondrial ribosomal protein L48) encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
Description
Rabbit Anti-MRP-L48 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MRPL48; CGI-118; HSPC290; 39S ribosomal protein L48; mitochondrial; L48mt; MRP-L48
Gene ID
51642
Accession Number
Q96GC5
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human MRP-L48 at AA range: 130-210
Clonality
Polyclonal
Tag
39S ribosomal protein L48 mitochondrial
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
23kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MRP-L48 Polyclonal Antibody detects endogenous levels of MRP-L48 protein.
Observed Molecular Weight
23
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
MRPL48; CGI-118; HSPC290; 39S ribosomal protein L48; mitochondrial; L48mt; MRP-L48
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q96GC5
Isotype
Rabbit IgG

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