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PAKα (phospho Ser199) Polyclonal Antibody

CAT: 0749-ABP55458-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55458-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PAK1 encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-PAKα (phospho Ser199) Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK
Gene ID
5058
Accession Number
Q13153
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from human PAKα around the phosphorylation site of S199
Clonality
Polyclonal
Tag
Serine threonine-protein kinase PAK 1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
61kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Phospho-PAKα (S199) Polyclonal Antibody detects endogenous levels of PAKα protein only when phosphorylated at S199.
Observed Molecular Weight
61
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13153
Isotype
Rabbit IgG

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