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MOR-1 Polyclonal Antibody

CAT: 0749-ABP55447-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55447-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OPRM1 encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR) . The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503. : c. 18A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for OPRM1. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.
Description
Rabbit Anti-MOR-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
OPRM1; MOR1; Mu-type opioid receptor; M-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOP
Gene ID
4988
Accession Number
P35372
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human MOR-1 at AA range: 40-120
Clonality
Polyclonal
Tag
Mu-type opioid receptor
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
48kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MOR-1 Polyclonal Antibody detects endogenous levels of MOR-1 protein.
Observed Molecular Weight
48
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
OPRM1; MOR1; Mu-type opioid receptor; M-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P35372
Isotype
Rabbit IgG

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