Products for Research Use Only

HnRNP M Polyclonal Antibody

CAT: 0749-ABP55331-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55331-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HNRNPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-hnRNP M Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HNRNPM; HNRPM; NAGR1; Heterogeneous nuclear ribonucleoprotein M; hnRNP M
Gene ID
4670
Accession Number
P52272
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human hnRNP M at AA range: 30-110
Clonality
Polyclonal
Tag
Heterogeneous nuclear ribonucleoprotein M
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
78kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HnRNP M Polyclonal Antibody detects endogenous levels of hnRNP M protein.
Observed Molecular Weight
78
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
HNRNPM; HNRPM; NAGR1; Heterogeneous nuclear ribonucleoprotein M; hnRNP M
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P52272
Isotype
Rabbit IgG